Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Take this medicine with food. Avoid taking antacids, H2-blockers, or proton pump inhibitors within 2 hours of taking this medicine. It is best to separate these medicines by 2 hours. Take your medicine at regular intervals. Do not take your medicine more often than directed. Take all of your medicine as directed even if you think you are better. Do not skip doses or stop your medicine early.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
• changes in hearing
• pain, tingling, numbness in the hands or feet
• signs and symptoms of heart failure like breathing problems; fast, irregular heartbeat; sudden weight gain; swelling of the ankles, feet; unusually weak or tired
• signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; right upper belly pain; yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• blurred vision
• diarrhea
• dizziness
• headache
• nausea, vomiting

Our pharmacists will check to see if this medication will cause any interactions with the information in your profile.

Do not take this medicine with any of the following medications:

• alfuzosin
• alprazolam
• avanafil
• certain medicines for blood pressure like felodipine, nisoldipine
• certain medicines for cholesterol like cerivastatin, lovastatin, simvastatin, lomitapide
• certain medicines for the heart like disopyramide, dofetilide, dronedarone, eplerenone, ivabradine, quinidine, ranolazine
• cisapride
• colchicine (if you have liver or kidney problems)
• conivaptan
• ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
• irinotecan
• isavuconazole
• lurasidone
• methadone
• midazolam
• naloxegol
• nevirapine
• other medicines that prolong the QT interval (cause an abnormal heart rhythm)
• pimozide
• red yeast rice
• sirolimus
• thioridazine
• ticagrelor
• triazolam

This medicine may also interact with the following medications:

• aliskiren
• amlodipine
• antacids
• antiviral medicines for HIV or AIDS
• aprepitant
• atorvastatin
• buprenorphine
• certain antibiotics like ciprofloxacin, clarithromycin, erythromycin
• certain medicines for bladder problems like fesoterodine, solifenacin, tolterodine
• certain medicines for cancer like axitinib, bortezomib, busulfan, dabrafenib, dasatinib, docetaxel, erlotinib, gefitinib, ibrutinib, imatinib, ixabepilone, lapatinib, nilotinib, ponatinib, sunitinib, trabectedin, trimetrexate, vinca alkaloids
• certain medicines for depression, anxiety, or psychotic disturbances like aripiprazole, buspirone, diazepam, haloperidol, perospirone, quetiapine, risperidone
• certain medicines for erectile dysfunction like vardenafil, sildenafil, tadalafil
• certain medicines for pain like alfentanil, fentanyl, oxycodone, sufentanil
• certain medicines for stomach problems like cimetidine, famotidine, omeprazole, lansoprazole
• certain medicines that treat or prevent blood clots like warfarin, dabigatran, rivaroxaban
• certain medicines for seizures like carbamazepine, phenytoin
• certain medicines for tuberculosis like isoniazid, INH, rifabutin, rifampin, rifapentine
• cilostazol
• cinacalcet
• cyclosporine
• digoxin
• eletriptan
• everolimus
• halofantrine
• isradipine
• meloxicam
• nadolol
• nifedipine
• other medicines for fungal infections
• praziquantel
• ramelteon
• repaglinide
• salmeterol
• saxagliptin
• steroid medicines like budesonide, ciclesonide, dexamethasone, fluticasone, methylprednisolone
• tacrolimus
• tamsulosin
• tolvaptan
• verapamil
• ziprasidone